Friday, March 31, 2006

Risks and benefits of omega 3 fats for mortality, cardiovascular disease, and cancer: systematic review

Risks and benefits of omega 3 fats for mortality, cardiovascular disease, and cancer: systematic review -- Hooper et al. 332 (7544): 752 -- BMJ:
"What is already known on this topic
A systematic review of randomised controlled trials in coronary heart disease showed reduced mortality in patients taking supplemental long chain omega 3 fats
What this study adds
This systematic review assessed the health effects of long chain and shorter chain omega 3 fats (together or separately) on total mortality, cardiovascular events, cancer, and strokes in a wide group of participants and found no evidence of a clear benefit of omega 3 fats on health"

Thursday, March 30, 2006

Pacto contra Corrupção

PNUD Brasil:
"Dois braços da ONU no Brasil, a maior organização de empresas pela responsabilidade social do país e a principal entidade de combate à corrupção lançaram nesta sexta-feira uma proposta conjunta que prevê que as companhias denunciem práticas de caixa dois no financiamento de eleições.
A proposta, intitulada Pacto Empresarial pela Integridade e Contra a Corrupção, está sendo apoiada pelo PNUD, pelo UNODC (Escritório das Nações Unidas contra Drogas e Crimes), pelo Instituto Ethos e pela Transparência Brasil. A minuta do texto, apresentada nesta sexta-feira na Bovespa (Bolsa de Valores de São Paulo), propõe que as empresas não só se comprometam a fazer doações em campanhas eleitorais apenas dentro dos “estritos limites da lei”, mas se obriguem a denunciar “qualquer irregularidade que venham a detectar”./.../"

Wednesday, March 29, 2006

The Effect Of Population Aging On Future Hospital Demand -- Strunk et al., 10.1377/hlthaff.25.w141 -- Health Affairs

The Effect Of Population Aging On Future Hospital Demand -- Strunk et al., 10.1377/hlthaff.25.w141 -- Health Affairs:
A simulation of future spending finds that aging will not be the strongest influence on inpatient hospital use.
by Bradley C. Strunk, Paul B. Ginsburg, and Michelle I. Banker
"ABSTRACT:

This analysis examines how shifts in the age distribution of the U.S. population, reflecting both the aging of the baby-boom generation and increased longevity, will affect demand for hospital inpatient services during the next ten years. Over that period, aging will drive about 0.74 percent annual growth in use of services. Aging's effect on inpatient demand varies by medical condition, with the highest rates of growth in services most used by elderly patients. Even for those services, however, aging is a much less important factor than local population trends and changing practice patterns attributable to advancing medical technology. [Health Affairs 25 (2006): w141-w149 (published online 28 March 2006; 10.1377/hlthaff.25.w141)]

A common theme permeating a wide range of contemporary health policy debates is the gradual aging of the U.S. population and its effect on the U.S. health care system. As a result of the baby-boom generation - the leading edge of which is now turning age sixty - the proportion of the U.S. population older than age sixty-five is projected to grow from 12.4 percent in 2005 to 14.5 percent in 2015 and 18.2 percent in 2025.1 Although the aging of the baby-boom generation is a key factor in the aging of the population as a whole, increasing life expectancy is also important./.../"

Tuesday, March 28, 2006

Social Determinants of Health: Bibliography

No Title: "Rachel's Democracy & Health News
February 18, 2006 (Draft 2)

SELECTED BIBLIOGRAPHY ON THE SOCIAL DETERMINANTS OF HEALTH

[My personal favorites are marked with a double asterisk. --PM]

By Peter Montague"

Monday, March 27, 2006

Karl Pearson

Karl Pearson - encyclopedia article about Karl Pearson.: "Karl Pearson was born in Islington, London on March 27, 1857, the son of barrister William Pearson and Fanny, née Smith. He was educated privately at University College School, after which he went to King's College, Cambridge to study mathematics. He then spent part of 1879 and 1880 studying medieval and 16th century German literature at the universities of Berlin and Heidelberg – in fact, he became sufficiently knowledgeable in this field that he was offered a post in the German department at Cambridge University. "

Sunday, March 26, 2006

Global Warming. Be Worred. Be Very Worried.

TIME.com Print Page: TIME Magazine -- Be Worred. Be Very Worried.: "Be Worred. Be Very Worried.
The climate is crashing, and global warming is to blame. Why the crisis hit so soon--and what we can do about it
By JEFFREY KLUGER
No one can say exactly what it looks like when a planet takes ill, but it probably looks a lot like Earth. Never mind what you've heard about global warming as a slow-motion emergency that would take decades to play out. Suddenly and unexpectedly, the crisis is upon us.
It certainly looked that way last week as the atmospheric bomb that was Cyclone Larry�a Category 5 storm with wind bursts that reached 180 m.p.h.�exploded through northeastern Australia. It certainly looked that way last year as curtains of fire and dust turned the skies of Indonesia orange, thanks to drought-fueled blazes sweeping the island nation. It certainly looks that way as sections of ice the size of small states calve from the disintegrating Arctic and Antarctic. And it certainly looks that way as the sodden wreckage of New Orleans continues to molder, while the waters of the Atlantic gather themselves for a new hurricane season just two months away. Disasters have always been with us and surely always will be. But when they hit this hard and come this fast - when the emergency becomes commonplace - something has gone grievously wrong. That something is global warming./.../ "

Thursday, March 23, 2006

Measuring Social Security’s

Measuring Social Scuritiy in an ageing world
Jagadeesh Gokhale & Kent Smetters
The U.S. Social Security program provides an important ‘½rst pillar’ of retirement income.1 Policymakers and the media, therefore, pay considerable attention to the ½nancial viability of the program. Each year, the Social Security trustees release a report that summarizes the ½nancial position of the Social Security program. Among other measures, the report draws attention to the program’s ‘crossover date’ (the year the program’s bene½t outlays will begin exceeding its tax receipts), the date of ‘trust fund exhaustion,’ and the present

The century ahead

The century ahead
On population ageing
(Chris Wilson)
The twentieth century was, above all else, a century of population growth; the twenty-½rst century will be a century of aging. Between 1900 and 2000 the world’s population quadrupled, from around 1.5 billion to over 6 billion.
Most of this increase occurred after World War II. At present, it seems unlikely that the population will grow by more than about a further 50 percent.
The most plausible forecasts see a population numbering between 9 and 10 billion by about 2050, with stability or decline in total population thereafter.

When Law and Ethics Collide -- Why Physicians Participate in Executions

NEJM -- When Law and Ethics Collide -- Why Physicians Participate in Executions: "On February 14, 2006, a U.S. District Court issued an unprecedented ruling concerning the California execution by lethal injection of murderer Michael Morales. The ruling ordered that the state have a physician, specifically an anesthesiologist, personally supervise the execution, or else drastically change the standard protocol for lethal injections.1 Under the protocol, the anesthetic sodium thiopental is given at massive doses that are expected to stop breathing and extinguish consciousness within one minute after administration; then the paralytic agent pancuronium is given, followed by a fatal dose of potassium chloride. "

Wednesday, March 22, 2006

WWAP | The UN World Water Development Report - Table of contents

WWAP The UN World Water Development Report - Table of contents
THE UN WORLD WATER DEVELOPMENT REPORT Water for People, Water for Life.
Website: http://www.unesco.org/water/wwap/wwdr/table_contents.shtml
UNESCO, March 22, 2006 -Although it is unevenly distributed, there is plenty of freshwater in the world. However, mismanagement, limited resources and environmental changes mean that almost one-fifth of the planet's population still lacks access to safe drinking water and 40% lack access to basic sanitation, says the United Nations World Water Development Report 2.
The triennial report is the most comprehensive assessment to date of freshwater resources. It was presented to the media in Mexico City on 9 March 2006. Entitled 'Water, a shared responsibility', this edition focuses on the importance of governance in managing the world's water resources and tackling poverty.
The UN World Water Development Report is the joint effort of 24 UN agencies and entities involved in water resources management. It is produced on their behalf by the UN World Water Assessment Programme (WWAP) whose secretariat is based at UNESCO. Its 15 chapters, each prepared by the various participating agencies, present a detailed analysis of the situation in all of the world's regions, backed up by the latest available data, maps and graphs, along with 17 case studies and numerous examples of good and bad practices in water governance.
'Water, a shared responsibility', will be formally presented by the UNESCO Director-General, on behalf of the United Nations, during the 4th World Water Forum (16-22 March) in Mexico City on 22 March, World Water Day.

IBGE - Instituto Brasileiro de Geografia e Estatística

IBGE - Instituto Brasileiro de Geografia e Estat�stica: "IBGE divulga perfil socioeconômico dos moradores em domicílios beneficiados por recebimento de dinheiro de programas sociais do governo
Em 2004, 15,6% dos domicílios no país tinham pelo menos um morador recebendo dinheiro de programa social do governo, sendo que na Região Nordeste este percentual chegou a 32%. Nesses domicílios beneficiados, 91% tinham rendimento domiciliar per capita1 de até um salário mínimo e 1,1% de mais de dois salários mínimos. Estas e outras informações fazem parte do suplemento da PNAD de 2004 sobre Acesso a Transferências de Renda de Programas Sociais, que inclui tabelas desagregadas por Grandes Regiões e Unidades da Federação."

The Citizens of Porto Alegre

The Citizens of Porto Alegre: "8 Marco is a self-employed handyman in his mid-30s who moved to the city of Porto Alegre from the Brazilian countryside eight years ago. A primary-school-educated son of a farmer, he�d had few opportunities in his small town and had heard about the city�s generous social services. He borrowed money for bus fare and landed in Porto Alegre, where he found construction work. But when his wages wouldn�t cover rent he headed for one of the squatter settlements on the outskirts of the city. He soon moved in with a companheira who sewed clothes and ironed from home. In time his life became more settled, with incremental improvements to the house, small but growing savings, and brisk business owing to his good reputation in the community. Marco�s story of migration, squatting, and survival was unremarkable�until he attended a local meeting on how the city government should invest its money in the region. /.../"

Conflitos de Interesses

Zero Hora: "Conflitos de interesses
ALOYZIO ACHUTTI/ Membro da Academia Sul-Rio-Grandense de Medicina

Conflitos - particularmente de interesses -, desde o nascimento há que enfrentá-los e aprender a gerenciá-los. Na medida em que nosso mundo se expande, em que a comunicação se desenvolve, quanto mais oportunidades de ter e de usufruir se nos oferecem, tanto mais apelos e decisões difíceis nos desafiam.
Para entender a complexidade do assunto é preciso examinar a semelhança da corrupção, não somente o lado do corrupto, mas também o papel do corruptor. Além dos conflitos naturais do quotidiano, a cultura na qual estamos imersos tem contribuído cada vez mais para aumentar tais situações, criando necessidades fictícias, aumentando as tentações reais e as fantasias.
Há quem diga que a medicina é uma profissão trágica porque encerra um permanente dilema, pois precisa acomodar três conjuntos de interesses que somente coincidem em área em geral muito restrita: interesses do paciente, da ciência e do próprio médico. A primazia tem que ser garantida ao paciente e cabe ao médico administrar o conflito.
Em geral, quando se discute o tema está se falando de pesquisa científica; da defesa, e discussão de controvérsias; e da prescrição médica. As tensões geradas pelo financiamento, incentivo e pressão gerencial da indústria e dos intermediários são tão grandes, que se adotou - para congressos e publicações - a norma, aparentemente saneadora, da declaração de potenciais conflitos. Na prática, entretanto, a declaração funciona às vezes como a transferência da responsabilidade (lavando as mãos) de quem está em conflito para quem vai receber a mensagem, não importam as potenciais confusões geradas e as dificuldades em separar o falso e duvidoso do verdadeiro ao interpretar as informações apresentadas...
Nem sempre o motivo do conflito é o dinheiro, muitas vezes é o poder, a vantagem política, a posição na hierarquia, o prazer, a própria vaidade pessoal.
Os conflitos se escondem atrás de muitas máscaras e pretextos que tentam justificá-los: paixão por uma causa ou projeto, defesa de princípios político-partidários, lobby, desenvolvimento científico e tecnológico, apoio a desenvolvimento artístico, confiança na família (nepotismo), propaganda e marketing etc. Não é suficiente e não adianta simplesmente declarar a existência potencial de conflito, nem alegar ignorância ou ausência de comprometimento. Existem ciladas naturais nas quais podem ficar enredados mesmo os de boa-fé.
Conflitos existem por toda parte e a solução não é simples. Qualquer decisão implica a satisfação de algum interesse em detrimento de outro, e para enfrentar dilemas os únicos remédios são: o respeito a princípios éticos, a transparência, a autenticidade e veracidade, o estabelecimento de prioridades e hierarquia de valores. De outra forma, mergulhamos na barbárie e não vale mais a pena cultuar a justiça, a verdade e a vida humana.

Tuesday, March 21, 2006

CELAFISCS

CELAFISCS

(Recomendado por Prof. Timóteo Araújo)
CELAFISCS - http://www.celafiscs.org.br
Acumule pelos menos 30 minutos de Atividade Física todos os dias -
Curso de Avaliação e Prescrição da Atividade Física - 27 a 29 Março 2006
III Forum de Boas Práticas na Promoção da Atividade Física para a População
5 de abril de 2006 das 8:30 às 14 h
xx11-4229-8990 ou 4229 9643

Monday, March 20, 2006

Fighting Tropical Diseases -- Sachs and Hotez 311 (5767): 1521 -- Science

Fighting Tropical Diseases -- Sachs and Hotez 311 (5767): 1521 -- Science: "The global fight against extreme poverty requires a solid partnership between physical scientists, social scientists, civil society, and policy-makers. For too long, extreme poverty has been viewed mainly or exclusively through the lens of economics and politics. Yet the root causes of extreme poverty involve science-based challenges requiring expertise in disciplines including disease ecology, medicine, public health, climatology, agronomy, and soil science. A new effort to control several of the major killer infectious diseases in Africa (www.earth.columbia.edu/malaria-ntd) illustrates the promise of a science-based policy approach to the fight against poverty, hunger, and disease."

NOAA/NGDC - Earth Observation Group - Defense Meteorological Satellite Progam, Boulder

NOAA/NGDC - Earth Observation Group - Defense Meteorological Satellite Progam, Boulder
(From Science)
This new map of Earth's nighttime illumination will make light bulb manufacturers glow and astronomers cringe. Released last month, the chart* from the National Geophysical Data Center (NGDC) in Boulder, Colorado, is a composite of satellite images snapped in 2003. Site visitors can download and compare images from as far back as 1992. Although changes in illumination often are hard to detect with the unaided eye, computer analysis shows that the United States and India continue to brighten, says Chris Elvidge of NGDC. However, areas of the former Soviet Union, such as Moldova and Ukraine, have been growing darker. You can peruse processed versions of the maps that highlight brightness differences at this site from a graduate student in Aachen, Germany.
* www.ngdc.noaa.gov/dmsp/download.html
www.blue-marble.de/night.php

Binding Database

Binding Database: "The BindingDB is a public, web-accessible database of measured binding affinities for biomolecules, genetically or chemically modified biomolecules, and synthetic compounds.The database currently contains data generated by isothermal titration calorimetry (ITC) and enzyme inhibition (Enz. Inhib.) methods; other techniques will be included in the future.
Scientists are encouraged to submit their published or accepted ITC and enzyme inhibiton data via the on-line forms. "

John Hawks Anthropology Weblog

John Hawks Anthropology Weblog
(From Science Netlog)
study suggesting that social stress leaves "molecular scars" on the brain and research exposing cultural diversity in gorillas are just two of the subjects that have snared the interest of anthropologist John Hawks of the University of Wisconsin, Madison. His wide-ranging blog excavates novel ideas and noteworthy discoveries in evolution, genetics, and human paleontology. Hawks promises to deliver three to five essays per week. Gems he's come across include a recent New York Times piece about the Soviet Union's unsuccessful efforts in the 1920s to prove our simian ancestry by crossbreeding chimps with humans. Readers intrigued by the tiny Flores hominid uncovered in Indonesia 2 years ago will find a section devoted to the controversial remains.
johnhawks.net/weblog

Sunday, March 19, 2006

WHO | Patients for patient safety

WHO Patients for patient safety: "The World Alliance for Patient Safety represents a major opportunity to put the patient and the consumer at the centre of the international movement to improve patient safety. Patients for Patient Safety, one of six action areas of the World Alliance, is designed to ensure that the perspective of patients and families, consumers and citizens - whichever term resonates best - is a central reference point in shaping this important work. This action area will be led by the patient safety consumer movement. /.../"

Expert Group on Poverty Statistics

Expert Group on Poverty Statistics: "The United Nations Statistical Commission, in its 28th Session of 1995, created a Group of Experts to study the statistical consequences of the World Summits of the United Nations on Population and Development (Cairo, 1994), on Social Development (Copenhagen, 1995) and the conditions of Women (Beijing, 1995) and to make proposals on the use of statistical information to follow up and monitor the objetives and goals approved in those summits. One outcome of this work was the recommendation, approved in the session of 1997, of a 'Minimum National Social Data Set' of indicators to be adopted by countries. "

Expert Group on Poverty Statistics

Expert Group on Poverty Statistics: "The United Nations Statistical Commission, in its 28th Session of 1995, created a Group of Experts to study the statistical consequences of the World Summits of the United Nations on Population and Development (Cairo, 1994), on Social Development (Copenhagen, 1995) and the conditions of Women (Beijing, 1995) and to make proposals on the use of statistical information to follow up and monitor the objetives and goals approved in those summits. One outcome of this work was the recommendation, approved in the session of 1997, of a 'Minimum National Social Data Set' of indicators to be adopted by countries. "

Saturday, March 18, 2006

Global Health Council - The Voice for Global Health

Global Health Council - The Voice for Global Health: "The Global Health Council is the world's largest membership alliance dedicated to saving lives by improving health throughout the world.

The Council works to ensure that all who strive for improvement and equity in global health have the information and resources they need to succeed."

Demos - A Network for Ideas & Action - About Demos

Demos - A Network for Ideas & Action - About Demos: "Demos' purpose is to help build a society where America can achieve its highest democratic ideals. We believe that requires a democracy that is robust and inclusive, with high levels of electoral participation and civic engagement, and an economy where prosperity and opportunity are broadly shared and disparity is reduced. Founded in 1999, Demos' work combines research with advocacy - melding the commitment to ideas of a think tank with the organizing strategies of an advocacy group.
We have four main program areas:
"

Friday, March 17, 2006

Origin and funding of the most frequently cited papers in medicine: database analysis -- Patsopoulos et al., 10.1136/bmj.38768.420139.80 -- BMJ

Origin and funding of the most frequently cited papers in medicine: database analysis -- Patsopoulos et al., 10.1136/bmj.38768.420139.80 -- BMJ
(recommended by Marcelo Gustavo Colominas [mgcolominas@gigared.com])
Results Of the 289 frequently cited articles, most had at least one author with a university (76%) or hospital (57%) affiliation, and the proportion of articles with each type of affiliation was constant over time. Government or public funding was most common (60% of articles), followed by industry (36%). The
proportion of most frequently cited articles funded by industry increased over time (odds ratio 1.17 per year, P = 0.001) and was equal to the proportion funded by government or public sources by 2001. 65 of the 77 most cited randomised controlled trials received funding from industry, and the proportion
increased significantly over time (odds ratio 1.59 per year, P = 0.003). 18 of the 32 most cited trials published after 1999 were funded by industry alone.
Conclusion Academic affiliations remain prominent among the authors of the most frequently cited medical research. Such research is increasingly funded by industry, often exclusively so.
Academics may be losing control of the clinical research agenda.

Sunday, March 12, 2006

Cobertura ACC - 2006

Cobertura ACC - 2006:
(Apud Cardioclick)
"ACC 2006: O papel átero-protetor e anti-inflamatório do HDL na doença cardiovascular

Atlanta, 11 de Março de 2006.

Nas sessões do simpósio satélite “The Emerging Role of HDL – Targeting Atherosclerosis Beyond HDL” dedicado ao papel do HDL no processo aterosclerótico, o Dr. Peter Libby, professor de Medicina da Harvard Medical School, destacou o papel da inflamação no processo aterosclerótico.

Estudos animais estabeleceram que a infusão de HDL ou a expressão aumentada de apoA-1 podem induzir a regressão das placas ateroscleróticas. Enzimas associadas ao HDL como a paraoxonase e fosfolipases podem reduzir o status oxidativo do LDL nas placas e também exercer outros efeitos anti-inflamatórios, anti-trombóticos e anti-apoptópicos. O HDL também pode reduzir o risco cardiovascular pelo papel de transporte reverso , removendo colesterol da parede arterial. “O aumento dos níveis de lipoproteína de alta densidade (HDL) e de sua principal apoliproteína A-1 (apoA-1) podem também ser um fator de contribuição na melhora dos parâmetros de pacientes tratados com estatinas.”, afirmou o palestrante.

Uma modalidade em estudo para terapêutica que vise aumento de HDL é a inibição da CEPT (proteína de transferência de colesterol esterificado)./.../"

Saturday, March 11, 2006

Ontario Health Promotion E-Bulletin

Ontario Health Promotion E-Bulletin:
"Sources for Health Promotion Definitions PDF Print E-mail
Friday, 03 March 2006
HP101
This OHPRS online course includes a Glossary at http://www.ohprs.ca/hp101/toolkit/gloss.htm."

Friday, March 10, 2006

Climate & Human Health

The Lancet: "There is near unanimous scientific consensus that greenhouse gas emissions generated by human activity will change Earth's climate. The recent (globally averaged) warming by 0·5°C is partly attributable to such anthropogenic emissions. Climate change will affect human health in many ways—mostly adversely. Here, we summarise the epidemiological evidence of how climate variations and trends affect various health outcomes. We assess the little evidence there is that recent global warming has already affected some health outcomes. We review the published estimates of future health effects of climate change over coming decades. Research so far has mostly focused on thermal stress, extreme weather events, and infectious diseases, with some attention to estimates of future regional food yields and hunger prevalence. An emerging broader approach addresses a wider spectrum of health risks due to the social, demographic, and economic disruptions of climate change. Evidence and anticipation of adverse health effects will strengthen the case for pre-emptive policies, and will also guide priorities for planned adaptive strategies."

Sunday, March 05, 2006

Mulheres da Restinga : Núcleo da Mama HMV

Comunicação Social:
(Enviado por Maira Caleffi - mairacal [mairacal@terra.com.br])
"Mulheres da Restinga são encaminhadas para mamografias

Mulheres que residem na Restinga terão a oportunidade hoje, 28, de realizar o exame de apalpação da mama, preventivo ao câncer, promovido pelo Núcleo da Mama de Porto Alegre. Os exames serão realizados das 10h às 16h, na escola de samba União da Tinga (Rua Álvaro Difini, 380, Restinga). A ação terá distribuição de brindes e corte de cabelo e objetiva o encaminhamento para exames de mamografia.

As mulheres devem portar as carteiras do posto e de identidade. Serão atendidas só as pertencentes às unidades básicas de saúde da Restinga. Trabalham na divulgação a Unidade Básica de Saúde Macedônia, a escola de samba União da Tinga e lideranças comunitárias. A iniciativa é do Núcleo Mama Porto Alegre, da Associação Hospitalar Moinhos de Vento, com apoio da Secretaria Municipal de Saúde (SMS) e Instituto da Mama de Porto Alegre."

Saturday, March 04, 2006

G A P M I N D E R: HOME

G A P M I N D E R: HOME
Making sense of the world by having fun with statistics!

Virchow - encyclopedia article

Friday, March 03, 2006

Medical Bankruptcy: Myth Versus Fact -- Dranove and Millenson, 10.1377/hlthaff.25.w74 -- Health Affairs

Medical Bankruptcy: Myth Versus Fact -- Dranove and Millenson, 10.1377/hlthaff.25.w74 -- Health Affairs: "
ABSTRACT:
David Himmelstein and colleagues recently contended that medical problems contribute to 54.5 percent of personal bankruptcies and threaten the solvency of solidly middle-class Americans. They propose comprehensive national health insurance as a solution. A reexamination of their data suggests that medical bills are a contributing factor in just 17 percent of personal bankruptcies and that those affected tend to have incomes closer to poverty level than to middle class. Moreover, for national health insurance to have an impact, it would have to define “medical” expenses in a much broader way than is now typical of either private or government-funded plans. [Health Affairs 25 (2006): w74–w83 (published online 28 February 2006; 10.1377/hlthaff.25.w74)]

The great enemy of the truth is very often not the lie—deliberate, contrived and dishonest—but the myth: persistent, persuasive and unrealistic.
—President John F. Kennedy, Commencement Address at Yale University, 11 June 1962.

It is no secret that bad health and bad debt often coincide. Unexpectedly large medical bills can impose a sizable burden on those who are already physically and economically fragile. In some cases, medical debt can contribute to a collapse of creditworthiness/.../"

Shifting dollars, saving lives: What might happen to mortality rates, and socio-economic inequalities in m

ScienceDirect - Social Science & Medicine : Shifting dollars, saving lives: What might happen to mortality rates, and socio-economic inequalities in mortality rates, if income was redistributed?: "Personal or household income predicts mortality risk, with each additional dollar of income conferring a slightly smaller decrease in the mortality risk. Regardless of whether levels of income inequality in a society impact on mortality rates over and above this individual-level association (i.e., the ‘income inequality hypothesis’), the current consensus is that narrowing income distributions will probably improve overall health status and reduce socio-economic inequalities in health. Our objective was to quantify this impact in a national population using 1.3 million 25–59-year-old respondents to the New Zealand 1996 census followed-up for mortality over 3 years.

We modelled 10–40% shifts of everyone's income to the mean income (equivalent to 10–40% reductions in the Gini coefficient). The strength of the income–mortality association was modelled using rate ratios from Poisson regression of mortality on the logarithm of equivalised household income, adjusted for confounders of age, marital status, education, car access, and neighbourhood socio-economic deprivation."

Thursday, March 02, 2006

Breast Cancer Risk Scented in Underarm Antiperspirants - CME Teaching Brief - MedPage Today

Breast Cancer Risk Scented in Underarm Antiperspirants - CME Teaching Brief - MedPage Today: "Breast Cancer Risk Scented in Underarm Antiperspirants "
  • Advise interested patients that a range of substances -- most of them organic -- have been shown to mimic estrogen, and may increase the risk of breast cancer.

  • Note that this review suggests that metal ions, including those derived from the aluminum salts in antiperspirants, may have similar effects, but advise patients that more research is needed to pin down any risks.

Wednesday, March 01, 2006

Furor on Mohammed drawings

U.N. conference tries to pacify furor created over Mohammed drawings
International leaders agreed that Muslim anger over the Mohammed cartoons is a symptom of a far more serious problem.
BY TANALEE SMITH
Associated Press
DOHA, Qatar - The furor over the Prophet Mohammed drawings is a small part of an expanding divide between Islam and the West, or what international leaders such as Archbishop Desmond Tutu describe as the ``symptom of a more serious disease.''
Attending a U.N.sponsored conference aimed at healing the deepening rift, Tutu and 19 other delegates agreed that key ways to bridge the chasm were reaching out to young people and providing more education. Even then, they agreed it would take years of dialogue and practical steps before the rift can be healed.
''What we face nowadays is not a clash of civilizations but a clash mostly caused by ignorance, arrogance, insensitivity and festering political differences that fuel hostilities,'' Turkish minister of state Mehmet Aydin said./.../

Health Inequalities Conference: Helsinki

Comparisons of life styles and living standards increasingly pay attention to non-income dimensions of well-being. Health in particular is recognized for both its intrinsic and instrumental value, contributing directly to an individual’s level of well-being as well as indirectly via its impact on other components. Substantial and widespread improvement in health outcomes has taken place during the past century. But despite this progress many individuals suffer health deprivation, with outcomes falling far short of those commonly accepted elsewhere. This conference will bring together researchers and practitioners, from both developed and developing countries, to analyze the causes and consequences of health deprivation and inequality, to examine patterns and trends in these outcomes, to evaluate alternative policy options, and to identify future research directions.
Conference topics will include:
• concepts and measures of health status• trends in health deprivation and inequality• causes of health deprivation and inequality• link between health and income deprivations• labour market outcomes and health status• nutrition and health• intra-household issues in health• evaluating alternative health policies

Rumsfwld Profits from Bird Flu Scare

Rumsfeld Profits From Bird Flu Scare

Excerpts " Among the beneficiaries of the run on Tamiflu is Secretary of Defense Donald Rumsfeld, who was chairman of Gilead from 1997 to 2001 and owns at least $5 million of the stock, which has jumped from $35 in April to $47. Former Secretary of State George Shultz, who is on Gilead's board, has sold more than $7 million worth of Gilead in 2005"...

Gilead developed Tamiflu on its own, then licensed it to Roche in 1996 to get help manufacturing and marketing it. But Gilead has complained for years that Roche wasn't aggressive on either front. In June, Gilead, which receives royalties equal to about 10% of Tamiflu sales, took the unusual step of terminating its licensing agreement with Roche and going into arbitration to win back exclusive rights to the drug.

Full article below

http://www.prisonplanet.com/articles/november2005/021105rumsfeldprofits.htm

Rumsfeld Profits From Bird Flu Scare

Fortune Magazine/Nelson D. Schwartz November 2 2005


A year ago Tamiflu was known, if at all, as an obscure remedy for influenza, which doctors typically treat with bed rest and chicken soup. Today, with panic mounting over a potential bird flu pandemic, it's the most sought-after drug in the world, as everyone from suburban soccer moms in the U.S. to health officials in London and Taipei scramble to stockpile the pill. At the moment, it seems, virtually the entire world is on sick-chicken alert.

"One dead parrot in the U.K. and four dead ducks in Romania does not mean the pandemic has arrived," says William Burns, head of the pharmaceutical division of Roche, the Swiss company that manufactures Tamiflu.. But the appearance in Europe of the H5N1 strain of bird flu—which has already infected 121 people in Asia, 62 fatally—has set off a stampede for the medicine and created a contagion of stock market speculation about Roche and the California biotech firm that first developed Tamiflu, Gilead Sciences. Despite worries about Tamiflu's effectiveness, the phenomenon is a reminder of just how quickly fear can spawn greed: The potential profit windfall for the drugmakers seems to be growing daily, and shares in both Roche and Gilead are surging.

Among the beneficiaries of the run on Tamiflu is Secretary of Defense Donald Rumsfeld, who was chairman of Gilead from 1997 to 2001 and owns at least $5 million of the stock, which has jumped from $35 in April to $47. Former Secretary of State George Shultz, who is on Gilead's board, has sold more than $7 million worth of Gilead in 2005.

As the bird-flu issue heated up earlier this year, according to a senior Pentagon official, Rumsfeld considered unloading his entire Gilead stake to avoid any perceived conflict of interest. He sought the advice of the Department of Justice, the Securities and Exchange Commission, and the federal Office of Government Ethics. When those agencies didn't offer an opinion, Rumsfeld consulted a private securities lawyer, who advised him to hold on to the stock and be vocal about his earlier recusal from all matters involving Gilead, rather than sell and run the risk of being accused of insider trading. Holding on has paid off—it's made the Pentagon chief, already one of the wealthiest members of the Bush cabinet, at least $1 million richer. In late October, Rumsfeld had the Pentagon's general counsel issue instructions on what he could and could not do in the event of an epidemic.

Gilead developed Tamiflu on its own, then licensed it to Roche in 1996 to get help manufacturing and marketing it. But Gilead has complained for years that Roche wasn't aggressive on either front. In June, Gilead, which receives royalties equal to about 10% of Tamiflu sales, took the unusual step of terminating its licensing agreement with Roche and going into arbitration to win back exclusive rights to the drug.

Roche CEO Franz Humer rejects Gilead's claims that his company neglected Tamiflu. He points out that Roche has doubled Tamiflu production since last year, and will double it again next year. What's more, Humer is confident the two companies will come up with a compromise that leaves Tamiflu in Roche's hands. The most likely scenario would be that Roche simply coughs up more in royalties to Gilead. That prospect has Wall Street very excited. Analyst Sapna Srivastava of Morgan Stanley says she's been getting calls from brokers who want to know whether to buy Tamiflu, as well as shares of Gilead. "It's suddenly become a stock everyone knows and talks about."

And interest goes well beyond Wall Street. Already drugstores are finding demand for the drug, well, contagious. "We've got doctors getting it for their families, sometimes a double treatment," says pharmacist Joseph Damin of Spencer Pharmacy in Scarsdale, N.Y. In late October, Roche halted delivery of the drug to the U.S. and Canada, to prevent hoarding and make sure there's still some Tamiflu left when the normal flu bug arrives this winter.

While the soccer moms may be going overboard, the people who really should be worrying about the threat seem remarkably blasé. Although governments in Europe are buying enough Tamiflu to cover a quarter of their population—and the Pentagon has already ordered $58 million worth of Tamiflu for U.S. troops around the world—the U.S. government has purchased only 4.3 million doses of Tamiflu and another anti-viral, Glaxo's Relenza, enough for just 1.5% of Americans. Despite months of debate about an additional multibillion-dollar purchase, Congress and the White House haven't agreed on a final plan.

Making tons of Tamiflu isn't easy. The drug is derived from the pods of Chinese star anise plants in a yearlong process that is expensive and dangerous—at one stage the stuff is highly explosive. "It's not like you press the button in the morning and in the afternoon Tamiflu falls out," says Humer. "We don't yet have a firm order from Washington ... words are not enough."
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